By Alton Meister
Advances in Enzymology and similar components of Molecular Biology is a seminal sequence within the box of biochemistry, supplying researchers entry to authoritative experiences of the newest discoveries in all components of enzymology and molecular biology. those landmark volumes date again to 1941, offering an unequalled view of the old improvement of enzymology. The sequence bargains researchers the most recent figuring out of enzymes, their mechanisms, reactions and evolution, roles in advanced organic method, and their program in either the laboratory and undefined. each one quantity within the sequence good points contributions by means of top pioneers and investigators within the box from all over the world. All articles are conscientiously edited to make sure thoroughness, caliber, and clarity.
With its wide variety of issues and lengthy ancient pedigree, Advances in Enzymology and comparable components of Molecular Biology can be utilized not just through scholars and researchers in molecular biology, biochemistry, and enzymology, but additionally by way of any scientist attracted to the invention of an enzyme, its homes, and its functions.
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Advances in Enzymology and comparable parts of Molecular Biology is a seminal sequence within the box of biochemistry, delivering researchers entry to authoritative stories of the most recent discoveries in all parts of enzymology and molecular biology. those landmark volumes date again to 1941, supplying an unmatched view of the old improvement of enzymology.
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Extra resources for Advances in Enzymology and Related Areas of Molecular Biology, Volume 37
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And DeWolfe, R. , J. Org. , 30, 1371 (1965). 83. , and Cordes, E. , J. Org. , 32, 2294 (1967). 84. , J. Chern. ( B ) ,1969, 1033. MECHANISM OF LYSOZYME ACTION 59 85. , Pletcher, T. , and Cordes, E. , Chem. , 1970, 527. 86. DeWolfe, R. , and Roberts, R. , J. Amer. Chem. , 76, 4379 (1954). 87. , Acta. Chem. , 24, 706 ( 1970). 88. ,J. Amer. Chenz. , 93, 2084 (1971). 89. , and Fife, T. , personal communication. 90. DeWolfe, R. , Ivanetich, K. , and Perry, N. , 1. Org. , 34, 848 (1969). 91. , and Smith, M.
50 BEN M. DUNN AND THOMAS C. BRUICE A direct comparison of the efficiency of intramolecular to intermolecular carboxyl group general acid catalysis has been made possible by the recent observations of Fife and Anderson with models 84 and 85 (120). Rate enhancements of 104 to lo6 are observed in 84 85 comparison of the o-carboxyl-substituted compounds relative to their ethyl esters or to the p-isomers, thus establishing that the effect is not electronic or steric in nature. , proton transfer occurs in the critical transition state).